5NEB

Structure of GluK1 ligand-binding domain (S1S2) in complex with LM-12b at 2.05 A resolution

Summary for 5NEB

Entry DOI	10.2210/pdb5neb/pdb
Descriptor	Glutamate receptor ionotropic, kainate 1, SULFATE ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	ionotropic glutamate receptor, kainate receptor, ligand-binding domain, gluk1, glur5, agonist, membrane protein
Biological source	Rattus norvegicus (Rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P22756
Total number of polymer chains	2
Total formula weight	59796.84
Authors	Moellerud, S.,Frydenvang, K.,Laulumaa, S.,Kastrup, J.S. (deposition date: 2017-03-10, release date: 2017-07-26, Last modification date: 2024-01-17)
Primary citation	Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors. ACS Chem Neurosci, 8:2056-2064, 2017 Cited by PubMed: 28691798 DOI: 10.1021/acschemneuro.7b00201 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation