5N5L

Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and [2-oxo-2-(1H-pyrrol-2-yl)ethyl] 5-bromo-1H-indole-3-carboxylate

Summary for 5N5L

• Entry DOI: 10.2210/pdb5n5l/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, Pimtide, 5-bromanyl-1~{H}-indole-3-carboxylic acid, ... (5 entities in total)
• Functional Keywords: serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 37637.57

Authors

Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-14, release date: 2018-03-07, Last modification date: 2024-01-17)

• Primary citation: Siefker, C.,Heine, A.,Taylor, C.,Kolb, P.,Hardes, K.,Steinmetzer, A.,Klebe, G.; A crystallographic fragment study with human Pim-1 kinase; to be published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)