5N5D
Crystal Structure of the O-Methyltransferase TomG from Streptomyces achromogenes involved in Tomaymycin synthesis in complex with SAM
Summary for 5N5D
| Entry DOI | 10.2210/pdb5n5d/pdb |
| Descriptor | Methyltransferase, (R,R)-2,3-BUTANEDIOL, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | o-methyltransferase, tomaymycin, rossmann-like fold, s-adenosyl methionine, transferase |
| Biological source | Streptomyces regensis |
| Total number of polymer chains | 2 |
| Total formula weight | 51157.80 |
| Authors | Pippel, J.,Blankenfeldt, W. (deposition date: 2017-02-13, release date: 2017-09-20, Last modification date: 2024-01-17) |
| Primary citation | von Tesmar, A.,Hoffmann, M.,Pippel, J.,Fayad, A.A.,Dausend-Werner, S.,Bauer, A.,Blankenfeldt, W.,Muller, R. Total Biosynthesis of the Pyrrolo[4,2]benzodiazepine Scaffold Tomaymycin on an In Vitro Reconstituted NRPS System. Cell Chem Biol, 24:1216-1227.e8, 2017 Cited by PubMed: 28890318DOI: 10.1016/j.chembiol.2017.08.001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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