5N5D
Crystal Structure of the O-Methyltransferase TomG from Streptomyces achromogenes involved in Tomaymycin synthesis in complex with SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Methyltransferase | polymer | 226 | 24622.9 | 2 | UniProt (A0A0J8AIC3) | Streptomyces regensis | |
| 2 | C, D, E, K, L (A, B) | (R,R)-2,3-BUTANEDIOL | non-polymer | 90.1 | 5 | Chemie (BU3) | |||
| 3 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | H, M (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 5 | I, J, N, O, P (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 488 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 222 (UniProt: A0A0J8AIC3)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Val 11 | Ala 11 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49245.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1912.0 | |
| All* | Total formula weight | 51157.8 |
