5N51

Crystal structure of human Pim-1 kinase in complex with a consensus peptide and fragment like molecule 3,4-Dibromothiophene-2-carboxylic acid

Summary for 5N51

Entry DOI	10.2210/pdb5n51/pdb
Descriptor	Serine/threonine-protein kinase pim-1, Pimtide, 3,4-bis(bromanyl)thiophene-2-carboxylic acid, ... (4 entities in total)
Functional Keywords	serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	37591.37
Authors	Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-11, release date: 2018-02-28, Last modification date: 2024-10-23)
Primary citation	Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G. A crystallographic fragment study with human Pim-1 kinase to be published,
Experimental method	X-RAY DIFFRACTION (2.118 Å)

Structure validation