cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-chlorobenzyl carbamimidothioate

Summary for 5N32

DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha-like protein, [azanyl-[(4-chlorophenyl)methylsulfanyl]methylidene]azanium, ... (5 entities in total)
Functional Keywordsfragment, complex, transferase, serine threonine kinase, camp, kinase, pka
Biological sourceCricetulus griseus (Chinese hamster)
Total number of polymer chains2
Total molecular weight43628.65
Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-08, release date: 2018-02-28, Last modification date: 2019-08-14)
Primary citation
Siefker, C.,Heine, A.,Klebe, G.
A crystallographic fragment study with cAMP-dependent protein kinase A
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2152 0.9% 0.4% 8.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-09-16