5MZL
Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule N-quinolin-5-ylpyridine-3-carboxamide
Summary for 5MZL
Entry DOI | 10.2210/pdb5mzl/pdb |
Descriptor | Serine/threonine-protein kinase pim-1, Pimtide, ~{N}-quinolin-5-ylpyridine-3-carboxamide, ... (5 entities in total) |
Functional Keywords | serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 2 |
Total formula weight | 37566.81 |
Authors | Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-01, release date: 2018-02-14, Last modification date: 2024-01-17) |
Primary citation | Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G. A crystallographic fragment study with human Pim-1 kinase to be published, |
Experimental method | X-RAY DIFFRACTION (1.955 Å) |
Structure validation
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