5MYW
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound SB-435634 at 1.77A resolution
Summary for 5MYW
Entry DOI | 10.2210/pdb5myw/pdb |
Descriptor | HTH-type transcriptional regulator EthR, ~{N}2-(1,3-benzodioxol-5-yl)benzene-1,2-diamine (3 entities in total) |
Functional Keywords | ethr, mycobacterium tuberculosis, transcription, represor |
Biological source | Mycobacterium tuberculosis H37Rv |
Total number of polymer chains | 1 |
Total formula weight | 25487.50 |
Authors | Blaszczyk, M.,Mendes, V.,Mugumbate, G.,Blundell, T.L. (deposition date: 2017-01-30, release date: 2017-10-25, Last modification date: 2024-01-17) |
Primary citation | Mugumbate, G.,Mendes, V.,Blaszczyk, M.,Sabbah, M.,Papadatos, G.,Lelievre, J.,Ballell, L.,Barros, D.,Abell, C.,Blundell, T.L.,Overington, J.P. Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach. Front Pharmacol, 8:681-681, 2017 Cited by PubMed: 29018348DOI: 10.3389/fphar.2017.00681 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.77 Å) |
Structure validation
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