5MYW

Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound SB-435634 at 1.77A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HTH-type transcriptional regulator EthR	polymer	228	25259.3	1	UniProt (P9WMC1) Pfam (PF00440) Pfam (PF21313) In PDB	Mycobacterium tuberculosis H37Rv
2	A	~{N}2-(1,3-benzodioxol-5-yl)benzene-1,2-diamine	non-polymer		228.2	1	Chemie (WCU)
3		water	water		18.0	66	Chemie (HOH)

Sequence modifications

A: 2 - 216 (UniProt: P9WMC1)

PDB	External Database	Details
Met -3	-	initiating methionine
Asp -2	-	expression tag
Ile -1	-	expression tag
Glu 0	-	expression tag
Phe 1	-	expression tag
Gly 217	-	expression tag
Ser 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25259.3
Non-Polymers*	Number of molecules	1
	Total formula weight	228.2
All*	Total formula weight	25487.5

*Water molecules are not included.