5MXD

BACE-1 IN COMPLEX WITH LIGAND 32397778

Summary for 5MXD

• Entry DOI: 10.2210/pdb5mxd/pdb
• Descriptor: Beta-secretase 1, ~{N},~{N}-dimethyl-2-pyrrolidin-1-yl-quinazolin-4-amine, CHLORIDE ION (3 entities in total)
• Functional Keywords: bace protease, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Membrane; Single-pass type I membrane protein: P56817
• Total number of polymer chains: 3
• Total formula weight: 145166.71

Authors

Alexander, R. (deposition date: 2017-01-23, release date: 2018-02-14, Last modification date: 2024-10-23)

• Primary citation: Alexander, R.; Human Beta Secretase 1 In Complex With Ligand 32397778; to be published,

Experimental method

X-RAY DIFFRACTION (2.52 Å)