5MVN

X-ray structure of the M205W mutant of GLIC in complex with propofol

5MVN の概要

• エントリーDOI: 10.2210/pdb5mvn/pdb
• 分子名称: Proton-gated ion channel, ACETATE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... (8 entities in total)
• 機能のキーワード: membrane protein, transport protein
• 由来する生物種: Gloeobacter violaceus PCC 7421
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 195759.51

構造登録者

Fourati, Z.,Delarue, M. (登録日: 2017-01-16, 公開日: 2018-02-14, 最終更新日: 2024-01-17)

• 主引用文献: Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M.; Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.; Cell Rep, 23:993-1004, 2018; PubMed: 29694907; DOI: 10.1016/j.celrep.2018.03.108

実験手法

X-RAY DIFFRACTION (3.49 Å)