5MR3

Crystal structure of red abalone egg VERL repeat 2 with linker in complex with sperm lysin at 1.8 A resolution

Summary for 5MR3

• Entry DOI: 10.2210/pdb5mr3/pdb
• Related: 1LIS 1LYN 2LIS 2LYN 3D4C 3D4G 3EF7 3NK3 3NK4 5II4 5II5 5II7 5II8 5II9 5IIA 5IIB 5IIC 5MR2
• Descriptor: Egg-lysin, Vitelline envelope sperm lysin receptor, GLYCEROL, ... (7 entities in total)
• Functional Keywords: cell adhesion, fertilization, egg-sperm interaction, gamete recognition, sperm receptor, egg coat, vitelline envelope, zp domain, zp-n domain, sperm acrosome, sperm penetration
• Biological source: Haliotis rufescens (California red abalone); More
• Cellular location: Cytoplasmic vesicle, secretory vesicle, acrosome lumen : P04552; Cell membrane ; Single-pass membrane protein : Q8WR62
• Total number of polymer chains: 8
• Total formula weight: 127899.42

Authors

Nishimura, K.,Raj, I.,Sadat Al-Hosseini, H.,De Sanctis, D.,Jovine, L. (deposition date: 2016-12-21, release date: 2017-06-14, Last modification date: 2024-01-17)

• Primary citation: Raj, I.,Sadat Al Hosseini, H.,Dioguardi, E.,Nishimura, K.,Han, L.,Villa, A.,de Sanctis, D.,Jovine, L.; Structural Basis of Egg Coat-Sperm Recognition at Fertilization.; Cell, 169:1315-1326.e17, 2017; PubMed: 28622512; DOI: 10.1016/j.cell.2017.05.033

Experimental method

X-RAY DIFFRACTION (1.8 Å)