5MQ1

Crystal structure of the BRD7 bromodomain in complex with BI-9564

Summary for 5MQ1

• Entry DOI: 10.2210/pdb5mq1/pdb
• Descriptor: Bromodomain-containing protein 7, 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one, ZINC ION, ... (7 entities in total)
• Functional Keywords: bromodomain, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Isoform 2: Nucleus: Q9NPI1
• Total number of polymer chains: 1
• Total formula weight: 14472.92

Authors

Diaz-Saez, L.,Martin, L.J.,Panagakou, I.,Picaud, S.,Krojer, T.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC) (deposition date: 2016-12-19, release date: 2018-01-17)

• Primary citation: Diaz-Saez, L.,Martin, L.J.,Panagakou, I.,Picaud, S.,Krojer, T.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC); Crystal structure of the BRD7 bromodomain in complex with BI-9564; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)