5MPV
Crystal structure of a Mycobacterium tuberculosis chorismate mutase optimized for high autonomous activity by directed evolution
Summary for 5MPV
| Entry DOI | 10.2210/pdb5mpv/pdb |
| Descriptor | Intracellular chorismate mutase (2 entities in total) |
| Functional Keywords | chorismate mutase, directed evolution, mycobacterium tuberculosis, isomerase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 1 |
| Total formula weight | 10063.80 |
| Authors | Thorbjornsrud, H.V.,Kamarauskaite, J.,Kast, P.,Krengel, U. (deposition date: 2016-12-19, release date: 2018-08-01, Last modification date: 2024-02-07) |
| Primary citation | Fahrig-Kamarauskait, J.,Wurth-Roderer, K.,Thorbjornsrud, H.V.,Mailand, S.,Krengel, U.,Kast, P. Evolving the naturally compromised chorismate mutase from Mycobacterium tuberculosis to top performance. J.Biol.Chem., 295:17514-17534, 2020 Cited by PubMed: 33453995DOI: 10.1074/jbc.RA120.014924 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
Download full validation report
