5MPV
Crystal structure of a Mycobacterium tuberculosis chorismate mutase optimized for high autonomous activity by directed evolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Intracellular chorismate mutase | polymer | 90 | 10063.8 | 1 | UniProt (P9WIC1) Pfam (PF01817) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | CM |
| 2 | B (D) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
D: 1 - 78 (UniProt: P9WIC1)
| PDB | External Database | Details |
|---|---|---|
| Leu 11 | Val 26 | engineered mutation |
| Val 15 | Asp 30 | engineered mutation |
| Gln 40 | Lys 55 | engineered mutation |
| Pro 52 | Thr 67 | engineered mutation |
| Asp 55 | Val 70 | engineered mutation |
| Ile 62 | Val 77 | engineered mutation |
| Val 72 | Asp 87 | engineered mutation |
| Leu 79 | - | expression tag |
| Leu 80 | - | expression tag |
| Leu 81 | - | expression tag |
| Arg 82 | - | expression tag |
| Leu 83 | - | expression tag |
| Gly 84 | - | expression tag |
| Arg 85 | - | expression tag |
| Gly 86 | - | expression tag |
| Pro 87 | - | expression tag |
| Asp 88 | - | expression tag |
| Ala 89 | - | expression tag |
| Met 90 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10063.8 | |
| All* | Total formula weight | 10063.8 |
