5MO9

Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20

5MO9 の概要

• エントリーDOI: 10.2210/pdb5mo9/pdb
• 分子名称: AB20 Fab heavy chain, AB20 Fab light chain, BDNF/NT-3 growth factors receptor, ... (4 entities in total)
• 機能のキーワード: trk receptor, antibody, antigen, complex, immune system
• 由来する生物種: Mus musculus (House mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 64516.75

構造登録者

Hoerer, S. (登録日: 2016-12-14, 公開日: 2017-08-02, 最終更新日: 2024-01-17)

• 主引用文献: Traub, S.,Stahl, H.,Rosenbrock, H.,Simon, E.,Florin, L.,Hospach, L.,Horer, S.,Heilker, R.; Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons.; J. Pharmacol. Exp. Ther., 361:355-365, 2017; PubMed: 28351853; DOI: 10.1124/jpet.117.240184

実験手法

X-RAY DIFFRACTION (2.594 Å)