Summary for 5MJ4
Entry DOI | 10.2210/pdb5mj4/pdb |
Related | 5MJ3 |
Descriptor | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ALPHABODY MA12, ... (4 entities in total) |
Functional Keywords | single-chain antiparallel triple-helix coiled-coil, immunoglobulin-like, 4-alpha helical bundle, antagonist, n-linked glycosylation, cytokine-antagonist complex, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 67351.65 |
Authors | Desmet, J.,Verstraete, K.,Bloch, Y.,Lorent, E.,Wen, Y.,Devreese, B.,Vandenbroucke, K.,Loverix, S.,Hettmann, T.,Deroo, S.,Somers, K.,Henderikx, P.,Lasters, I.,Savvides, S. (deposition date: 2016-11-29, release date: 2017-01-11, Last modification date: 2024-01-17) |
Primary citation | Desmet, J.,Verstraete, K.,Bloch, Y.,Lorent, E.,Wen, Y.,Devreese, B.,Vandenbroucke, K.,Loverix, S.,Hettmann, T.,Deroo, S.,Somers, K.,Henderikx, P.,Lasters, I.,Savvides, S. STRUCTURAL BASIS OF IL-23 ANTAGONISM BY AN ALPHABODY PROTEIN Nature Communications, 5:5237-, 2014 Cited by PubMed: 25354530DOI: 10.1038/NCOMMS6237 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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