5MHK

ICP4 DNA-binding domain in complex with 19mer DNA duplex from its own promoter

Summary for 5MHK

• Entry DOI: 10.2210/pdb5mhk/pdb
• Descriptor: DNA (5'-D(*GP*CP*TP*CP*CP*GP*TP*GP*TP*GP*GP*AP*CP*GP*AP*TP*CP*GP*G)-3'), RS1, ICP4 DNA BINDING DOMAIN, ... (8 entities in total)
• Functional Keywords: transcription factor, herpes virus, intercalation, transcription
• Biological source: Human herpesvirus 1 (HHV-1); More
• Total number of polymer chains: 9
• Total formula weight: 122027.32

Authors

Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P. (deposition date: 2016-11-24, release date: 2017-05-24, Last modification date: 2019-04-10)

• Primary citation: Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, A.P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P.; The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.; Nucleic Acids Res., 45:8064-8078, 2017; PubMed: 28505309; DOI: 10.1093/nar/gkx419

Experimental method

X-RAY DIFFRACTION (2.28 Å)