5MH6
D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-ketohexanoic acid and NAD+ (1.35 A resolution)
Summary for 5MH6
Entry DOI | 10.2210/pdb5mh6/pdb |
Related | 5MH5 |
Descriptor | D-2-hydroxyacid dehydrogenase, 1,2-ETHANEDIOL, SULFATE ION, ... (8 entities in total) |
Functional Keywords | d-2-hydroxyacid dehydrogenase, halophile, chiral specificity, reaction mechanism, oxidoreductase |
Biological source | Haloferax mediterranei ATCC 33500 |
Total number of polymer chains | 4 |
Total formula weight | 139025.28 |
Authors | Bisson, C.,Baker, P.J.,Domenech Perez, J.,Pramanpol, N.,Harding, S.E.,Rice, D.W.,Ferrer, J. (deposition date: 2016-11-23, release date: 2018-06-06, Last modification date: 2024-06-19) |
Primary citation | Domenech Perez, J.,Pramanpol, N.,Baker, P.J.,Bisson, C.,Harding, S.E.,Rice, D.W.,Ferrer, J. Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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