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5MH6

D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-ketohexanoic acid and NAD+ (1.35 A resolution)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
D-2-hydroxyacid dehydrogenasepolymer30833368.04UniProt (Q2VEQ7)
Pfam (PF02826)
Haloferax mediterranei ATCC 33500D2-HDH,D-specific 2-hydroxyacid dehydrogenase
2AA, AB, BB, CB, DB...
(B, D, A, C)
1,2-ETHANEDIOLnon-polymer62.122Chemie (EDO)
3BA, EB, K, QA
(B, D, A, C)
SULFATE IONnon-polymer96.14Chemie (SO4)
4CA, DA, EA, FA, FB...
(B, D, A, C)
MAGNESIUM IONnon-polymer24.324Chemie (MG)
5HA, KB, S, XA
(B, D, A, C)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.44Chemie (NAD)
6IA, LB, T, YA
(B, D, A, C)
2-Ketohexanoic acidnon-polymer130.14Chemie (7N5)
7JA, ZA
(C, D)
SODIUM IONnon-polymer23.02Chemie (NA)
8MB, NB, OB, PB
(A, B, C, D)
waterwater18.01738Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight133472.0
Non-Polymers*Number of molecules60
Total formula weight5553.3
All*Total formula weight139025.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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