5MGZ
Streptomyces Spheroides NovO (8-demethylnovbiocic acid methyltransferase) with SAH
Summary for 5MGZ
Entry DOI | 10.2210/pdb5mgz/pdb |
Descriptor | 8-demethylnovobiocic acid C(8)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL, ... (5 entities in total) |
Functional Keywords | c methyltransferase, novobiocin biosynthesis, sam dependent, transferase |
Biological source | Streptomyces niveus |
Total number of polymer chains | 2 |
Total formula weight | 53435.12 |
Authors | Chung, C.-W.,Mosley, J.,Sadler, J.C. (deposition date: 2016-11-22, release date: 2017-01-18, Last modification date: 2024-05-08) |
Primary citation | Sadler, J.C.,Chung, C.H.,Mosley, J.E.,Burley, G.A.,Humphreys, L.D. Structural and Functional Basis of C-Methylation of Coumarin Scaffolds by NovO. ACS Chem. Biol., 12:374-379, 2017 Cited by PubMed: 28068060DOI: 10.1021/acschembio.6b01053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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