5MFS

The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one

5MFS の概要

• エントリーDOI: 10.2210/pdb5mfs/pdb
• 分子名称: Aminopeptidase N, ZINC ION, [(7~{S})-6,6-bis(oxidanyl)-4-phenyl-5,7,8,9-tetrahydrobenzo[7]annulen-7-yl]azanium, ... (9 entities in total)
• 機能のキーワード: m1 aminopeptidase, hydrolase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 104315.88

構造登録者

Peng, G.,Olieric, V.,McEwen, A.G.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C. (登録日: 2016-11-18, 公開日: 2017-04-19, 最終更新日: 2024-01-17)

• 主引用文献: Peng, G.,McEwen, A.G.,Olieric, V.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C.; Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis.; Proteins, 85:1413-1421, 2017; PubMed: 28383176; DOI: 10.1002/prot.25301

実験手法

X-RAY DIFFRACTION (1.57 Å)