5MER

Human Leukocyte Antigen A02 presenting ILAKFLHEL

5MER の概要

• エントリーDOI: 10.2210/pdb5mer/pdb
• 分子名称: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ILE-LEU-ALA-LYS-PHE-LEU-HIS-GLU-LEU, ... (9 entities in total)
• 機能のキーワード: immune system, hla, tcr, cross-reactivity, telomerase, hla a02
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01892; Secreted . Note=(Microbial infection) In the presence of M: P61769
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 93171.40

構造登録者

Rizkallah, P.J.,Lloyd, A.,Crowther, M.,Cole, D.K.,Sewell, A.K. (登録日: 2016-11-16, 公開日: 2016-12-07, 最終更新日: 2024-01-17)

• 主引用文献: Cole, D.K.,van den Berg, H.A.,Lloyd, A.,Crowther, M.D.,Beck, K.,Ekeruche-Makinde, J.,Miles, J.J.,Bulek, A.M.,Dolton, G.,Schauenburg, A.J.,Wall, A.,Fuller, A.,Clement, M.,Laugel, B.,Rizkallah, P.J.,Wooldridge, L.,Sewell, A.K.; Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.; J. Biol. Chem., 292:802-813, 2017; PubMed: 27903649; DOI: 10.1074/jbc.M116.741603

実験手法

X-RAY DIFFRACTION (1.88 Å)