5M78

Human Carbonic Anhydrase II in complex with fragment-like inhibitor.

Summary for 5M78

Entry DOI	10.2210/pdb5m78/pdb
Descriptor	Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... (6 entities in total)
Functional Keywords	protein-ligand-complex, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	30409.95
Authors	Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2016-10-27, release date: 2017-12-20, Last modification date: 2024-01-17)
Primary citation	Glockner, S.,Heine, A.,Klebe, G. A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II. Biomolecules, 10:-, 2020 Cited by PubMed: 32235320 DOI: 10.3390/biom10040518 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.077 Å)

Structure validation