5M78
Human Carbonic Anhydrase II in complex with fragment-like inhibitor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Carbonic anhydrase 2 | polymer | 265 | 29806.6 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | A | MERCURIBENZOIC ACID | non-polymer | 321.7 | 1 | Chemie (MBO) | |||
5 | A | 2-HYDROXYBENZOIC ACID | non-polymer | 138.1 | 1 | Chemie (SAL) | |||
6 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Pro -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29806.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 603.4 | |
All* | Total formula weight | 30410.0 |