5M5G

Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2)

Summary for 5M5G

• Entry DOI: 10.2210/pdb5m5g/pdb
• Descriptor: putative polycomb protein EED, Putative uncharacterized protein, HISTONE H3 11-Mer peptide, ... (7 entities in total)
• Functional Keywords: transferase, repressive, complex
• Biological source: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719); More
• Total number of polymer chains: 4
• Total formula weight: 175871.17

Authors

Zhang, Y.,Justin, N.,Wilson, J.,Gamblin, S. (deposition date: 2016-10-21, release date: 2017-01-11, Last modification date: 2019-10-16)

• Primary citation: Zhang, Y.,Justin, N.,Wilson, J.R.,Gamblin, S.J.; Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".; Science, 354:1543-1543, 2016; PubMed: 28008037; DOI: 10.1126/science.aaf6236

Experimental method

X-RAY DIFFRACTION (2.27 Å)