5LYJ
Tubulin-Combretastatin A4 complex
Summary for 5LYJ
Entry DOI | 10.2210/pdb5lyj/pdb |
Related | 4O2B |
Descriptor | Tubulin alpha-1B chain, Combretastatin A4, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (13 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, cell cycle- inhibitor complex |
Biological source | Rattus norvegicus (Norway Rat) More |
Cellular location | Cytoplasm, cytoskeleton: P81947 Q6B856 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 265286.93 |
Authors | Gaspari, R.,Prota, A.E.,Cavalli, A.,Steinmetz, M.O. (deposition date: 2016-09-28, release date: 2017-01-18, Last modification date: 2024-01-17) |
Primary citation | Gaspari, R.,Prota, A.E.,Bargsten, K.,Cavalli, A.,Steinmetz, M.O. Structural basis of cis- and trans-combretastatin binding to tubulin Chem, 2017 Cited by DOI: 10.1016/j.chempr.2016.12.005PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.397 Å) |
Structure validation
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