5LUD
Structure of Cyclophilin A in complex with 2,3-Diaminopyridine
Summary for 5LUD
Entry DOI | 10.2210/pdb5lud/pdb |
Descriptor | Peptidyl-prolyl cis-trans isomerase, pyridine-2,3-diamine (3 entities in total) |
Functional Keywords | isomerase, ligand complex, beta barrel, prolyl cis/trans isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18145.63 |
Authors | McNae, I.W.,Nowicki, M.W.,Blackburn, E.A.,Wear, M.A.,Walkinshaw, M.D. (deposition date: 2016-09-08, release date: 2017-04-05, Last modification date: 2024-01-17) |
Primary citation | Wear, M.A.,Nowicki, M.W.,Blackburn, E.A.,McNae, I.W.,Walkinshaw, M.D. Thermo-kinetic analysis space expansion for cyclophilin-ligand interactions - identification of a new nonpeptide inhibitor using BiacoreTM T200. FEBS Open Bio, 7:533-549, 2017 Cited by PubMed: 28396838DOI: 10.1002/2211-5463.12201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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