5LSJ

CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C delta-HEAD2 COMPLEX

Summary for 5LSJ

• Entry DOI: 10.2210/pdb5lsj/pdb
• Descriptor: Protein MIS12 homolog, Polyamine-modulated factor 1, Kinetochore-associated protein DSN1 homolog, ... (5 entities in total)
• Functional Keywords: alpha-helical, cell cycle
• Biological source: Homo sapiens (Human); More
• Cellular location: Chromosome, centromere, kinetochore : Q9H081; Nucleus : Q6P1K2 Q9H410 Q96IY1 Q03188
• Total number of polymer chains: 10
• Total formula weight: 173558.23

Authors

Vetter, I.R.,Petrovic, A.,Keller, J.,Liu, Y. (deposition date: 2016-09-02, release date: 2016-11-16, Last modification date: 2024-01-17)

• Primary citation: Petrovic, A.,Keller, J.,Liu, Y.,Overlack, K.,John, J.,Dimitrova, Y.N.,Jenni, S.,van Gerwen, S.,Stege, P.,Wohlgemuth, S.,Rombaut, P.,Herzog, F.,Harrison, S.C.,Vetter, I.R.,Musacchio, A.; Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.; Cell, 167:1028-1040.e15, 2016; PubMed: 27881301; DOI: 10.1016/j.cell.2016.10.005

Experimental method

X-RAY DIFFRACTION (3.25 Å)