5LRF
Crystal structure of Glycogen Phosphorylase b in complex with KS389
Summary for 5LRF
Entry DOI | 10.2210/pdb5lrf/pdb |
Related | 5LRE |
Descriptor | Glycogen phosphorylase, muscle form, (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | transferase, alpha and beta protein |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98409.33 |
Authors | Kantsadi, A.L.,Leonidas, D.D. (deposition date: 2016-08-18, release date: 2017-06-14, Last modification date: 2019-02-20) |
Primary citation | Kantsadi, A.L.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Solovou, T.G.A.,Kun, S.,Bokor, E.,Somsak, L.,Leonidas, D.D. van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase. J. Struct. Biol., 199:57-67, 2017 Cited by PubMed: 28483603DOI: 10.1016/j.jsb.2017.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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