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5LRF

Crystal structure of Glycogen Phosphorylase b in complex with KS389

Summary for 5LRF
Entry DOI10.2210/pdb5lrf/pdb
Related5LRE
DescriptorGlycogen phosphorylase, muscle form, (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywordstransferase, alpha and beta protein
Biological sourceOryctolagus cuniculus (Rabbit)
Total number of polymer chains1
Total formula weight98409.33
Authors
Kantsadi, A.L.,Leonidas, D.D. (deposition date: 2016-08-18, release date: 2017-06-14, Last modification date: 2019-02-20)
Primary citationKantsadi, A.L.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Solovou, T.G.A.,Kun, S.,Bokor, E.,Somsak, L.,Leonidas, D.D.
van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
J. Struct. Biol., 199:57-67, 2017
Cited by
PubMed: 28483603
DOI: 10.1016/j.jsb.2017.05.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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