5LRD

Crystal structure of Glycogen Phosphorylase b in complex with KS242

Summary for 5LRD

• Entry DOI: 10.2210/pdb5lrd/pdb
• Related: 5lrc
• Descriptor: Glycogen phosphorylase, muscle form, (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-(4-methylphenyl)-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: transferase, alpha and beta protein
• Biological source: Oryctolagus cuniculus (Rabbit)
• Total number of polymer chains: 1
• Total formula weight: 98147.13

Authors

Kantsadi, A.L.,Leonidas, D.D. (deposition date: 2016-08-18, release date: 2017-06-14, Last modification date: 2017-06-28)

• Primary citation: Kantsadi, A.L.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Solovou, T.G.A.,Kun, S.,Bokor, E.,Somsak, L.,Leonidas, D.D.; van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.; J. Struct. Biol., 199:57-67, 2017; PubMed: 28483603; DOI: 10.1016/j.jsb.2017.05.001

Experimental method

X-RAY DIFFRACTION (1.8 Å)