5LRC

Crystal structure of Glycogen Phosphorylase in complex with KS114

Summary for 5LRC

Entry DOI	10.2210/pdb5lrc/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, (1S)-1,5-anhydro-1-(5-phenyl-4H-1,2,4-triazol-3-yl)-D-glucitol, ... (4 entities in total)
Functional Keywords	transferase, alpha and beta protein
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	97845.65
Authors	Kantsadi, A.L.,Stravodimos, G.A.,Chatzileontiadou, D.S.M.,Leonidas, D.D. (deposition date: 2016-08-18, release date: 2017-06-14, Last modification date: 2020-08-05)
Primary citation	Kantsadi, A.L.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Solovou, T.G.A.,Kun, S.,Bokor, E.,Somsak, L.,Leonidas, D.D. van der Waals interactions govern C-beta-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase. J. Struct. Biol., 199:57-67, 2017 Cited by PubMed: 28483603 DOI: 10.1016/j.jsb.2017.05.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation