5LLV

Crystal structure of DACM F87M/L110M Transthyretin mutant

Summary for 5LLV

Entry DOI	10.2210/pdb5llv/pdb
Descriptor	Transthyretin, CHLORIDE ION, ACETATE ION, ... (4 entities in total)
Functional Keywords	tetramer, protein aggregation, n-(7-dimethylamino-4-methylcoumarin-3-yl))maleimide, transport protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P02766
Total number of polymer chains	4
Total formula weight	55985.00
Authors	Sala, B.M.,Ghadami, S.A.,Bemporad, F.,Chiti, F.,Ricagno, S. (deposition date: 2016-07-28, release date: 2017-06-07, Last modification date: 2024-01-10)
Primary citation	Ghadami, S.A.,Bemporad, F.,Sala, B.M.,Tiana, G.,Ricagno, S.,Chiti, F. FRET studies of various conformational states adopted by transthyretin. Cell. Mol. Life Sci., 74:3577-3598, 2017 Cited by PubMed: 28478513 DOI: 10.1007/s00018-017-2533-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation