5LI1
Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain
Summary for 5LI1
Entry DOI | 10.2210/pdb5li1/pdb |
Descriptor | Protein kinase C iota type, Par-3 partitioning defective 3 homolog (C. elegans), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (7 entities in total) |
Functional Keywords | apkc, polarity, complex, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm : P41743 |
Total number of polymer chains | 2 |
Total formula weight | 43990.64 |
Authors | Soriano, E.V.,Purkiss, A.G.,McDonald, N.Q. (deposition date: 2016-07-13, release date: 2016-09-14, Last modification date: 2024-01-10) |
Primary citation | Soriano, E.V.,Ivanova, M.E.,Fletcher, G.,Riou, P.,Knowles, P.P.,Barnouin, K.,Purkiss, A.,Kostelecky, B.,Saiu, P.,Linch, M.,Elbediwy, A.,Kjr, S.,O'Reilly, N.,Snijders, A.P.,Parker, P.J.,Thompson, B.J.,McDonald, N.Q. aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization. Dev.Cell, 38:384-398, 2016 Cited by PubMed: 27554858DOI: 10.1016/j.devcel.2016.07.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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