5LG3

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with chlorpromazine

5LG3 の概要

• エントリーDOI: 10.2210/pdb5lg3/pdb
• 分子名称: Gamma-aminobutyric-acid receptor subunit beta-1, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine (2 entities in total)
• 機能のキーワード: ion channel, transport protein, membrane protein
• 由来する生物種: Dickeya dadantii (strain 3937)
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 357022.31

構造登録者

Nys, M.,Wijckmans, E.,Farinha, A.,Brams, M.,Spurny, R.,Ulens, C. (登録日: 2016-07-05, 公開日: 2016-10-26, 最終更新日: 2024-01-31)

• 主引用文献: Nys, M.,Wijckmans, E.,Farinha, A.,Yoluk, O.,Andersson, M.,Brams, M.,Spurny, R.,Peigneur, S.,Tytgat, J.,Lindahl, E.,Ulens, C.; Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.; Proc.Natl.Acad.Sci.USA, 113:E6696-E6703, 2016; PubMed: 27791038; DOI: 10.1073/pnas.1603101113

実験手法

X-RAY DIFFRACTION (3.567 Å)