5LB9

Structure of the T175V Etr1p mutant in the monoclinic form P21

Summary for 5LB9

Entry DOI	10.2210/pdb5lb9/pdb
Descriptor	Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial, GLYCEROL, SULFATE ION, ... (6 entities in total)
Functional Keywords	negative catalysis, enzyme, nadp, mitochondria, mutant, crotonyl-coa, reductase, oxidoreductase
Biological source	Candida tropicalis (Yeast)
Cellular location	Mitochondrion : Q8WZM3
Total number of polymer chains	2
Total formula weight	86788.08
Authors	Wagner, T.,Rosenthal, R.G.,Voegeli, B.,Shima, S.,Erb, T.J. (deposition date: 2016-06-15, release date: 2017-05-10, Last modification date: 2024-01-10)
Primary citation	Rosenthal, R.G.,Vogeli, B.,Wagner, T.,Shima, S.,Erb, T.J. A conserved threonine prevents self-intoxication of enoyl-thioester reductases. Nat. Chem. Biol., 13:745-749, 2017 Cited by PubMed: 28504678 DOI: 10.1038/nchembio.2375 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation