5LAX
Crystal structure of HLA_DRB1*04:01 in complex with alpha-enolase peptide 26-40
Summary for 5LAX
Entry DOI | 10.2210/pdb5lax/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-4 beta chain, alpha-enolase peptideTSKGLFRAAVPSGAS, ... (5 entities in total) |
Functional Keywords | hla, autoimmune desease, rheumathoid arthritis, mhc class ii, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P13760 |
Total number of polymer chains | 6 |
Total formula weight | 93034.18 |
Authors | Dubnovitsky, A.,Kozhukh, G.,Sandalova, T.,Achour, A. (deposition date: 2016-06-15, release date: 2016-12-07, Last modification date: 2024-01-10) |
Primary citation | Gerstner, C.,Dubnovitsky, A.,Sandin, C.,Kozhukh, G.,Uchtenhagen, H.,James, E.A.,Ronnelid, J.,Ytterberg, A.J.,Pieper, J.,Reed, E.,Tandre, C.,Rieck, M.,Zubarev, R.A.,Ronnblom, L.,Sandalova, T.,Buckner, J.H.,Achour, A.,Malmstrom, V. Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis. Front Immunol, 7:494-494, 2016 Cited by PubMed: 27895642DOI: 10.3389/fimmu.2016.00494 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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