5L1H
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor GYKI53655
Summary for 5L1H
Entry DOI | 10.2210/pdb5l1h/pdb |
Related | 5L1B 5L1E 5L1F 5L1G |
Descriptor | Glutamate receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, (8R)-5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-2H,7H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide (3 entities in total) |
Functional Keywords | transporter, membrane protein, transport protein, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 361517.32 |
Authors | Yelshanskaya, M.V.,Singh, A.K.,Sampson, J.M.,Sobolevsky, A.I. (deposition date: 2016-07-29, release date: 2016-10-19, Last modification date: 2023-10-04) |
Primary citation | Yelshanskaya, M.V.,Singh, A.K.,Sampson, J.M.,Narangoda, C.,Kurnikova, M.,Sobolevsky, A.I. Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91:1305-1315, 2016 Cited by PubMed: 27618672DOI: 10.1016/j.neuron.2016.08.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.801 Å) |
Structure validation
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