5KT7
Teranry complex of human DNA polymerase iota(1-445) inserting dCMPNPP opposite template G in the presence of Mn2+
Summary for 5KT7
Entry DOI | 10.2210/pdb5kt7/pdb |
Related | 5KT2 5KT3 5KT4 5KT5 5KT6 |
Descriptor | DNA (5'-D(P*TP*GP*GP*GP*GP*TP*CP*CP*T)-3'), DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3'), DNA polymerase iota, ... (5 entities in total) |
Functional Keywords | dna polymerase, poli, manganese, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 55453.47 |
Authors | Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P. (deposition date: 2016-07-11, release date: 2016-08-31, Last modification date: 2024-03-06) |
Primary citation | Choi, J.Y.,Patra, A.,Yeom, M.,Lee, Y.S.,Zhang, Q.,Egli, M.,Guengerich, F.P. Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase iota. J.Biol.Chem., 291:21063-21073, 2016 Cited by PubMed: 27555320DOI: 10.1074/jbc.M116.748285 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.151 Å) |
Structure validation
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