5KT7

Teranry complex of human DNA polymerase iota(1-445) inserting dCMPNPP opposite template G in the presence of Mn2+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue MN P 901

Chain	Residue
A	ASP34
A	ASP126
A	GLU127
A	0KX501
A	MN502
P	DC873

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site_id	AC2
Number of Residues	18
Details	binding site for residue 0KX A 501

Chain	Residue
A	CYS37
A	PHE38
A	TYR39
A	VAL64
A	THR65
A	TYR68
A	ARG71
A	LYS77
A	ASP126
A	LYS214
A	MN502
P	DC873
P	MN901
T	DG840
T	DG841
A	ASP34
A	LEU35
A	ASP36

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site_id	AC3
Number of Residues	5
Details	binding site for residue MN A 502

Chain	Residue
A	ASP34
A	LEU35
A	ASP126
A	0KX501
P	MN901

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00216

Chain	Residue	Details
A	GLU127

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:27555320, ECO:0007744|PDB:5KT5

Chain	Residue	Details
A	ASP34
A	LEU35
A	ASP126

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15254543, ECO:0007744|PDB:1T3N

Chain	Residue	Details
A	TYR39
A	ARG71

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