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5KFP

Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mg2+ for 600s

Summary for 5KFP
Entry DOI10.2210/pdb5kfp/pdb
Related5KFA 5KFB 5KFC 5KFD 5KFE 5KFF 5KFG 5KFH 5KFI 5KFJ 5KFK 5KFL 5KFM 5KFN 5KFO 5KFQ 5KFR 5KFS 5KFT 5KFU 5KFV 5KFW 5KFX 5KFY 5KFZ 5KG0 5KG1 5KG2 5KG3 5KG4 5KG5 5KG6 5KG7
DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*(DS))-3'), ... (9 entities in total)
Functional Keywordsin crystallo reaction, dna polymerase, metal ion dependent catalysis, replication, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight56081.45
Authors
Gao, Y.,Yang, W. (deposition date: 2016-06-12, release date: 2016-06-22, Last modification date: 2023-09-27)
Primary citationGao, Y.,Yang, W.
Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352:1334-1337, 2016
Cited by
PubMed: 27284197
DOI: 10.1126/science.aad9633
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

數據於2024-03-27公開中

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