5KFP

Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mg2+ for 600s

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue MG A 501

Chain	Residue
A	ASP13
P	AS9
A	ASP115
A	GLU116
A	CA502
A	MG503
A	MG504
A	STP508
A	HOH680
P	DT8

---

site_id	AC2
Number of Residues	8
Details	binding site for residue CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	MG504
A	STP508
A	DPO509
P	AS9

---

site_id	AC3
Number of Residues	8
Details	binding site for residue MG A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	MG504
A	STP508
A	DPO509
P	AS9

---

site_id	AC4
Number of Residues	9
Details	binding site for residue MG A 504

Chain	Residue
A	ASP13
A	MG501
A	CA502
A	MG503
A	STP508
A	DPO509
A	HOH680
A	HOH797
P	AS9

---

site_id	AC5
Number of Residues	10
Details	binding site for residue GOL A 505

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH641
A	HOH690
A	HOH711
A	HOH752

---

site_id	AC6
Number of Residues	8
Details	binding site for residue GOL A 506

Chain	Residue
A	GLU94
A	ALA95
A	GLU98
A	ARG303
A	HOH639
A	HOH645
A	HOH661
A	HOH724

---

site_id	AC7
Number of Residues	10
Details	binding site for residue GOL A 507

Chain	Residue
A	ASN26
A	HIS28
A	GLY271
A	ILE272
A	GLU273
A	TYR274
A	GLU277
A	HOH607
A	HOH609
A	HOH648

---

site_id	AC8
Number of Residues	30
Details	binding site for residue STP A 508

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MG501
A	CA502
A	MG503
A	MG504
A	DPO509
A	HOH606
A	HOH628
A	HOH652
A	HOH680
A	HOH797
P	DT8
P	AS9
P	HOH105
P	HOH110
T	DT3
T	DT4
T	DA5

---

site_id	AC9
Number of Residues	19
Details	binding site for residue DPO A 509

Chain	Residue
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	CA502
A	MG503
A	MG504
A	STP508
A	HOH606
A	HOH628
A	HOH652
A	HOH797
P	AS9
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	TYR52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KFO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27284197","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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