5KEL

EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6

5KEL の概要

• エントリーDOI: 10.2210/pdb5kel/pdb
• 関連するPDBエントリー: 5KEM 5KEN
• EMDBエントリー: 8240 8241 8242
• 分子名称: Ebola surface glycoprotein, GP1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: ebola virus surface glycoprotein, therapeutic antibody cocktail, zmapp, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Zaire ebolavirus (strain Mayinga-76) (ZEBOV); 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 359998.05

構造登録者

Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe Jr., J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B. (登録日: 2016-06-09, 公開日: 2016-09-07, 最終更新日: 2020-07-29)

• 主引用文献: Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe, J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B.; Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.; Nat Microbiol, 1:16128-16128, 2016; PubMed: 27562261; DOI: 10.1038/nmicrobiol.2016.128

実験手法

ELECTRON MICROSCOPY (4.3 Å)