5KDO
Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the Gbeta1-Ggamma1
Summary for 5KDO
Entry DOI | 10.2210/pdb5kdo/pdb |
Related | 5KDL |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ... (5 entities in total) |
Functional Keywords | heterotrimeric g protein g protein coupled receptors g protein activation g protein structure gdp release, signaling protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 3 |
Total formula weight | 87100.40 |
Authors | Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (deposition date: 2016-06-08, release date: 2016-08-03, Last modification date: 2023-09-27) |
Primary citation | Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E. A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor. J.Biol.Chem., 291:19674-19686, 2016 Cited by PubMed: 27462082DOI: 10.1074/jbc.M116.745513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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