5K8V

Crystal Structure of Mus musculus Protein Arginine Methyltransferase 4 (CARM1 130-487) with CP1

5K8V の概要

• エントリーDOI: 10.2210/pdb5k8v/pdb
• 分子名称: Histone-arginine methyltransferase CARM1, [[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethylamino]-azanyl-methylidene]azanium, 1,2-DIMETHOXYETHANE, ... (7 entities in total)
• 機能のキーワード: protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• 由来する生物種: Mus musculus (Mouse)
• 細胞内の位置: Nucleus: Q9WVG6
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 165884.52

構造登録者

Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J. (登録日: 2016-05-31, 公開日: 2016-11-09, 最終更新日: 2024-01-10)

• 主引用文献: Cura, V.,Marechal, N.,Troffer-Charlier, N.,Strub, J.M.,van Haren, M.J.,Martin, N.I.,Cianferani, S.,Bonnefond, L.,Cavarelli, J.; Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors.; FEBS J., 284:77-96, 2017; PubMed: 27879050; DOI: 10.1111/febs.13953

実験手法

X-RAY DIFFRACTION (2.25 Å)