5K5S
Crystal structure of the active form of human calcium-sensing receptor extracellular domain
Summary for 5K5S
Entry DOI | 10.2210/pdb5k5s/pdb |
Related | 5K5T |
Descriptor | Extracellular calcium-sensing receptor, TRYPTOPHAN, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | venus flytrap module, cysteine-rich domain, homodimer, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 140698.29 |
Authors | Geng, Y.,Mosyak, L.,Kurinov, I.,Zuo, H.,Sturchler, E.,Cheng, T.C.,Subramanyam, P.,Brown, A.P.,Brennan, S.C.,Mun, H.-C.,Bush, M.,Chen, Y.,Nguyen, T.,Cao, B.,Chang, D.,Quick, M.,Conigrave, A.,Colecraft, H.M.,McDonald, P.,Fan, Q.R. (deposition date: 2016-05-23, release date: 2016-08-03, Last modification date: 2020-07-29) |
Primary citation | Geng, Y.,Mosyak, L.,Kurinov, I.,Zuo, H.,Sturchler, E.,Cheng, T.C.,Subramanyam, P.,Brown, A.P.,Brennan, S.C.,Mun, H.C.,Bush, M.,Chen, Y.,Nguyen, T.X.,Cao, B.,Chang, D.D.,Quick, M.,Conigrave, A.D.,Colecraft, H.M.,McDonald, P.,Fan, Q.R. Structural mechanism of ligand activation in human calcium-sensing receptor. Elife, 5:-, 2016 Cited by PubMed: 27434672DOI: 10.7554/eLife.13662 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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