5K3N

Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209

Summary for 5K3N

• Entry DOI: 10.2210/pdb5k3n/pdb
• Related: 5K38 5K3L 5K3M
• Descriptor: Nuclear receptor ROR-gamma, (3S)-3-(2H-1,3-benzodioxol-5-yl)-1-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one (3 entities in total)
• Functional Keywords: double helix, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P51449
• Total number of polymer chains: 4
• Total formula weight: 116651.22

Authors

Huang, P.,Rastinejad, F.,Lu, J. (deposition date: 2016-05-19, release date: 2017-05-31, Last modification date: 2024-03-06)

• Primary citation: Huang, P.,Rastinejad, F.; Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209; To be published,

Experimental method

X-RAY DIFFRACTION (2.666 Å)