5K3N
Crystal structure of Retinoic acid receptor-related orphan receptor (ROR) gamma ligand binding domain complex with ML209
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004879 | molecular_function | nuclear receptor activity |
| D | 0005634 | cellular_component | nucleus |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue 6Q6 A 600 |
| Chain | Residue |
| A | GLN286 |
| A | HIS323 |
| A | ALA327 |
| A | LEU362 |
| A | MET365 |
| A | PHE388 |
| A | ILE400 |
| A | HIS479 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 6Q6 B 600 |
| Chain | Residue |
| B | HIS323 |
| B | LEU324 |
| B | LEU362 |
| B | MET365 |
| B | VAL376 |
| B | PHE378 |
| B | PHE388 |
| B | ILE400 |
| B | HIS479 |
| B | GLN286 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue 6Q6 C 600 |
| Chain | Residue |
| C | GLN286 |
| C | HIS323 |
| C | ALA327 |
| C | LEU362 |
| C | MET365 |
| C | PHE388 |
| C | ILE400 |
| C | HIS479 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue 6Q6 D 600 |
| Chain | Residue |
| D | GLN286 |
| D | HIS323 |
| D | LEU324 |
| D | LEU362 |
| D | MET365 |
| D | PHE378 |
| D | PHE388 |
| D | HIS479 |
