5JWE

Crystal structure of H-2Db in complex with the LCMV-derived GP92-101 peptide

5JWE の概要

• エントリーDOI: 10.2210/pdb5jwe/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Pre-glycoprotein polyprotein GP complex, ... (6 entities in total)
• 機能のキーワード: immunology, antigen presentation, mhc class i, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Stable signal peptide: Virion membrane ; Multi-pass membrane protein . Glycoprotein G1: Virion membrane ; Peripheral membrane protein . Glycoprotein G2: Virion membrane ; Single-pass membrane protein : P09991
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 182387.37

構造登録者

Buratto, J.,Badia-Martinez, D.,Norstrom, M.,Sandalova, T.,Achour, A. (登録日: 2016-05-12, 公開日: 2017-05-24, 最終更新日: 2024-01-10)

• 主引用文献: Hafstrand, I.,Badia-Martinez, D.,Josey, B.J.,Norstrom, M.,Buratto, J.,Pellegrino, S.,Duru, A.D.,Sandalova, T.,Achour, A.; Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.; PLoS ONE, 12:e0189584-e0189584, 2017; PubMed: 29253009; DOI: 10.1371/journal.pone.0189584

実験手法

X-RAY DIFFRACTION (2.4 Å)